Heteroduplex Analyses
《英文msh詞典》Heteroduplex Analyses
[入口詞] Heteroduplex Analyses
[主題詞] Heteroduplex Analysis
[英文釋義] A method of detecting gene mutation by mixing PCR-amplified mutant and wild-type DNA followed by denaturation and reannealing. The resultant products are resolved by gel electrophoresis,with single base substitutions detectable under optimal electrophoretic conditions and gel formulations. Large base pair mismatches may also be analyzed by using electron microscopy to visualize heteroduplex regions.